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Paternity test : ウィキペディア英語版
DNA paternity testing
DNA paternity testing is the use of DNA profiling (known as genetic fingerprinting) to determine whether two individuals are biologically parent and child. A paternity test establishes genetic proof whether a man is the biological father of an individual, and a maternity test establishes whether a woman is the biological mother of an individual. Tests can also determine the likelihood of someone being a biological grandparent to a grandchild. Though genetic testing is the most reliable standard, older methods also exist, including ABO blood group typing, analysis of various other proteins and enzymes, or using human leukocyte antigen antigens. The current techniques for paternity testing are using polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP). Paternity testing can now also be performed while the woman is still pregnant from a blood draw. 〔("A Non-invasive Test to Determine Paternity in Pregnancy" New England Journal of Medicine May 3, 2012 )〕〔("Paternity Blood Tests That Work Early in a Pregnancy" New York Times June 20, 2012 )〕
DNA testing is currently the most advanced and accurate technology to determine parentage. In a DNA parentage test, the result (called the 'probability of parentage)〔("Probability of Paternity" Dr. Ron Ostrowski, UNC Charlotte )〕 is 0% when the alleged parent is not biologically related to the child and the probability of parentage is typically 99.99% when the alleged parent is biologically related to the child. However, while almost all individuals have a single and distinct set of genes, rare individuals, known as "chimeras", have at least two different sets of genes, which can result in a false negative result if their reproductive tissue has a different genetic make-up from the tissue sampled for the test.
==Paternity or maternity testing for child or adult==
The testing is performed by collecting buccal cells found on the inside of a person's cheek using a Buccal swab or cheek swab. These swabs have wooden or plastic stick handles with a cotton on synthetic tip. The collector rubs the inside of a person's cheek in order to collect as many Buccal cells as possible. The Buccal cells are then sent to a laboratory for testing. For paternity testing, samples from the alleged father and child would be needed. For maternity testing, samples from the alleged mother and child would be needed.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「DNA paternity testing」の詳細全文を読む



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